Research Images and Annotations are from the MERI 2017 Calendar


Dr. Richard R. Dubielzig featured on NPR and in the Wisconsin State Journal

Dr. Richard R. Dubielzig, who founded the Comparative Ocular Pathology Laboratory of Wisconsin (COPLOW), was recently featured in this NPR story and in the Wisconsin State Journal.


Stem Cell Therapies: The Hope and the Hype

With stem cells the focus of much recent attention in the media, this statement from Dr. David Gamm clarifies both the promise and the misconceptions about stem cell use for vision therapies.  And keep in mind the 10 Things to Know Before You Fall Victim to a Retinal Stem Cell Scam.


Dr. Jose-Alain Sahel Gives 5th Annual McPherson Endowed Lecture

Picture of Jose-Alain Sahel, PhD, MD
Dr. José-Alain Sahel, MD, PhD

Approximately 150 people heard Dr. Jose-Alain Sahel deliver the 5th Annual McPherson Endowed Lecture on Thursday, April 27th. Dr. Sahel's talked ranged widely over his work in recent decades, with particular emphasis on maintaining cone function in retinal degenerations.

Cone functional loss is the key event leading to blindness in rod-cone dystrophies.  Dr. Sahel's lab embarked on a "fishing expedition" aimed at identifying the mechanisms underlying this loss, turning up potential clues for therapies aiming at preserving/restoring light-adapted and central vision in these patients. With collaborators Thierry Leveillard and Saddek Mohand-Said, Dr. Sahel discovered Rod-derived Cone Viability Factor, identified its receptor, and demonstrated its potential therapeutic benefit in several animal models, paving the way to upcoming clinical trials. This strategy has been extended to attempt to restore cone or inner retinal function by optogenetics. In depth phenotyping will guide the selection of target populations of patients that might benefit from these strategies; the development of novel, real life, functional outcome measurements will be needed to demonstrate its therapeutic value.

5th Annual Lecture FlyerDr. José-Alain Sahel, MD, PhD, is Professor and Chairman of the Department of Ophthalmology at the University of Pittsburgh Medical Center.  He holds The Eye and Ear Foundation Endowed Chair of Ophthalmology in the University of Pittsburgh Medical School.  Dr. Sahel is also the Director of Institut de la Vision at the Pierre et Marie Curie Medical School, Sorbonne Universites/Inserm/CNRS, Centre Hospitalier National d'Ophtalmologie, Paris.


Protein Discovery

Dr. Akihiro Ikeda

Dr. Akihiro Ikeda, Professor of Medical Genetics and RRF Walter H. Helmerich Research Chair at the McPherson Eye Research Institute, has published a study of a novel protein that could lead to potential new treatments for age-related retinal diseases. Read more

Photoreceptor Replacement Research

Dr. David Gamm

Dr. David Gamm gave an overview of the current state of photoreceptor replacement research at Wednesday Nite @ the Lab in February. Watch the video.


New Opportunity: Vision Science Instructional Lectures


Thank you for making Cycle for Sight 2017 successful!