Bird, A., B. Blodi, E. Chew, T. Clemons, G. Comer, I. Constable, D. Eliott, S. Farsiu, M. Friedlander, M. Gillies, R. Guymer, J. Hubschman, G. Jaffe, C. Johnson, E. Lad, P. Rosenfeld, L. Singerman, H. Wiley, and J. Yan. Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients With Macular Telangiectasia Type 2: A Randomized Clinical Trial. Ophthalmology, 2018, p. Epub PubMed Text.
Abstract
Purpose: To test the effects of an encapsulated cell-based delivery of a neuroprotective agent, ciliary neurotrophic factor (CNTF), on progression of macular telangiectasia type 2, a neurodegenerative disease with no proven effective therapy.