Li, J., L. Zhao, G. Urabe, Y. Fu, and L. Guo. Epigenetic Intervention With a BET Inhibitor Ameliorates Acute Retinal Ganglion Cell Death in Mice. Mol Vis, 2017, p. PubMed Text.
Abstract
Purpose: The bromo and extraterminal (BET) epigenetic “reader” family is becoming an appealing new therapeutic target for several common diseases, yet little is known of its role in retinal neurodegeneration. We explored the potential of BET inhibition in the protection of retinal ganglion cells (RGCs).