In Vivo Adaptive Bayesian Regularized Lagrangian Carotid Strain Imaging for Murine Carotid Arteries and Its Associations With Histological Findings

Eickhoff, J., K. Eliceiri, M. Graham, C. Korcarz, Y. Liu, C. Mitchell, R. Mukaddim, J. Stein, M. Tattersall, T. Varghese, and A. Weichmann. In Vivo Adaptive Bayesian Regularized Lagrangian Carotid Strain Imaging for Murine Carotid Arteries and Its Associations With Histological Findings. Ultrasound Med Biol, 2023, p. Epub PubMed Text.

Abstract

Objectives: Non-invasive methods for monitoring arterial health and identifying early injury to optimize treatment for patients are desirable. The objective of this study was to demonstrate the use of an adaptive Bayesian regularized Lagrangian carotid strain imaging (ABR-LCSI) algorithm for monitoring of atherogenesis in a murine model and examine associations between the ultrasound strain measures and histology.

Keywords: Adaptive Bayesian regularization; Atherosclerosis; Cardiovascular disease; Carotid elastography; Carotid strain imaging; High-frequency ultrasound; Murine model.