Halbach, P., D. Pillers, N. York, M. Asuma, M. Chiu, W. Luo, S. Tokarz, I. Bird, and B. Pattnaik. Oxytocin Expression and Function in the Posterior Retina: A Novel Signaling Pathway. Invest Ophthalmol Vis Sci, 2015, p. PubMed Text.
Abstract
Purpose: Oxytocin (OXT) is recognized as an ubiquitously acting nonapeptide hormone that is involved in processes ranging from parturition to neural development. Its effects are mediated by cell signaling that occurs as a result of oxytocin receptor (OXTR) activation. We sought to determine whether the OXT-OXTR signaling pathway is also expressed within the retina.
Keywords: GPCR; cell-calcium; neuropeptide; oxytocin receptor; retinal pigment epithelium; signaling.