Ripolles-Garcia, A., N. Dolgova, M. Phillips, S. Savina, A. Ludwig, S. Stuedemann, J. Wolfe, O. Garden, D. Gamm, G. Aguirre, and W. Beltran. Triple Drug Immunosuppression for Xenotransplantation of Human Photoreceptor Precursor Cells in the Canine Retina. Investigative Ophthalmology & Visual Science, 2022, p. Epub Full Text.
Abstract
Purpose
To evaluate the effect of a systemic multidrug immunosuppressive protocol on the survival and integration of hESC-derived photoreceptor precursor cells (PRPCs) transplanted into the subretinal space (SRS) of normal and degenerated canine retinas.