Zebrafish Rfx4 controls dorsal and ventral midline formation in the neural tube

Sedykh, I., A. Keller, B. Yoon, L. Roberson, O. Moskvin, and Y. Grinblat. Zebrafish Rfx4 Controls Dorsal and Ventral Midline Formation in the Neural Tube. Dev Dyn, 2018, p. PubMed Text.

Abstract

Background: Rfx winged-helix transcription factors, best known as key regulators of core ciliogenesis, also play ciliogenesis-independent roles during neural development. Mammalian Rfx4 controls neural tube morphogenesis via both mechanisms.

Keywords: Hh signaling; Rfx4; Zic; foxa2; neural tube; zebrafish.