Enes Akyuz, PhD
Credentials: Department of Pediatrics (Pattnaik lab)
Position title: Scientist I
Email: eakyuz@wisc.edu
Website: Google Scholar page
Address:
200 N Charter St, #106
Madison, WI 53715
Research
My key focus of research is channelopathy, defects in inwardly rectifying potassium channel 7.1 (Kir7.1) proteins, leading to congenital blindness. I am working on the mutations in retinal pigment epithelium Kir7.1 channels cause blindness such as Leber congenital amaurosis (LCA). I am currently doing several in-vitro (HEK293 and patient-derived induced pluripotent stem cells iPSC-RPE) and in-vivo (genetically engineered mouse) models to study cell, tissue, organ, and animal physiology. I am using techniques like patch-clamp, biological imaging, molecular techniques to repair Kir7.1 channel defects in the hope to treat blindness.