Sushmita Roy, PhD
Credentials: Associate Professor, Department of Biostatistics & Medical Informatics, Wisconsin Institute for Discovery
Email: sroy@biostat.wisc.edu
Website: Roy Lab
Phone: (608) 316-4453
Address:
Wisconsin Institute for Discovery
330 Orchard St
Madison, WI 53715
Education:
BE 2000, Computer Engineering, University of Pune, Pune, India
MS 2005, Computer Science, University of New Mexico, Albuquerque, NM
PhD 2009, Computer Science, University of New Mexico, Albuquerque, NM
Postdoctoral 2009-2012, Computational Biology, Broad Institute, Cambridge, MA
Research Interests:
Dr. Roy is collaborating with David Gamm to study the transcriptional programs of retinal development as well as regulatory networks that might be involved in cell fate decisions in rod versus cone cells. She is also a co-investigator on a UO1 grant led by Kris Saha, together with David Gamm, the goal of which is to examine disruptions in transcriptional regulatory programs due to off-target effects of CRISPR-based treatments. As one of the molecular readouts this project will measure single cell RNA-seq data. Her group has been developing clustering and molecular network inference and analysis tools for RNA-seq and array data, and has started to apply and develop new tools to single cell RNA-seq data. Together with Profs. Gamm and Saha, they are applying these tools to multiple single cell RNA-seq data to examine how CRISPR or other small scale genetic perturbations change the overall transcriptional state of retinal cells.