Researchers find the tipping point at which compensatory measures in a diseased retinal circuit shift from beneficial to detrimental
A recent study by the Hoon lab published in Current Biology has uncovered new modes of retinal circuit compensation and adaptation in response to impairments seen in congenital stationary night blindness (CSNB). CSNB is a retinal disease where input to a primary retinal pathway is suppressed. Using mouse models that mimic different stages of disease severity, partial …